FLYCAST
FLYCAST / EXPERIMENT 001|COMPUTATIONAL CONNECTOMICS

Can a fruit fly predict the future?

Run your time series through the wiring diagram of a real biological nervous system. 166,691 biological neurons. One frozen connectome. Your data.

YOUR SIGNALTime Series
166K CNS NODESRecurrent Reservoir
FORECASTDirect Readout
Published CNS Neurons
...
Runtime: ... nodes
Structural Synapses
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W[post, pre] sparse CSR
Sensory Inputs
...
Annotated sensory bodies
Readout Electrodes
...
Linear Ridge mapping
01 / Concept & Thesis

What happens when you turn an insect nervous system into a computer?

In 2026, researchers published the MaleCNS v1.0 connectome — a complete synapse-resolution electron-microscopy reconstruction of an entire male adult fruit-fly central nervous system, containing over 166,000 neurons and 25.5 million directed synaptic connections spanning the brain, optic lobes, and ventral nerve cord.

FlyCast treats this biological wiring diagram as a fixed recurrent computational reservoir (an Echo State Network). Rather than training billions of artificial weights, the biological wiring remains completely frozen.

When your time-series values arrive, they stimulate 512 annotated sensory neurons. The signal ripples through the actual recurrent synaptic graph, creating rich nonlinear spatial-temporal trajectories.

Only a lightweight linear Ridge readout is trained to map sampled internal network states to your future target values. If the fly predicts better than standard autoregression, the biological wiring provided genuine computational utility. If it fails, the application honestly tells you so.

1INPUT INJECTION

Chronological data is standardized and deterministically mapped across 512 sensory CNS neurons.

2FROZEN CNS

Activity propagates through 25.58M real directed synaptic edges via leaky tanh rate dynamics.

3STATE SAMPLING

4,096 virtual electrodes sample internal recurrent state vectors across the connectome at each step.

4DIRECT READOUT

A multi-output Ridge regression learns to project internal states into multi-step future horizons.

02 / READY EXPERIMENTS

Try a benchmark signal through the connectome

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Does biological wiring outperform classical models?

Every FlyCast run measures real held-out RMSE against persistence and autoregressive baselines. If the fly wins, you see it. If the fly loses, we display that honestly.